1. The study of the clinical effects of ultraviolet blood irradiation in 445 consecutive and unselected cases of acute pyogenic infections has been made. Confirmation of our original preliminary findings was observed. These findings showed that ultraviolet blood irradiation was a rapid, efficient and non-specific control of all types of acute pyogenic infections (except bacterial endocarditis), the use of which was characterized by a quick subsidence of toxic symptoms, a disappearance of bacterial proliferation and invasion and an uneventful convalescence.

2. In seventy-four consecutive and unselected cases of virus or virus-like infections we have observed results comparable to the favorable effects observed in its use in acute pyogenic infections.

3. It was found that sulfa sensitive infections are easily and favorably influenced by ultraviolet blood irradiation and that a large variety of infections not controlled by sulfa drugs can be rapidly and efficiently controlled by ultraviolet blood irradiation .

4. Many penicillin-resistant infections respond favorably to ultraviolet blood irradiation , both the acute pyogenic types and the virus or virus-like infections.

5. We were able to confirm the preoperative protective effect of ultraviolet blood irradiation described by Rebbeck and fittingly called the Rebbeck Effect.

6. There is no contraindication to the joint use of penicillin and ultraviolet blood irradiation , but sulfa drugs cannot be safely used in the first four or five days following ultraviolet blood irradiation .