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Critical path in cardiac stem cell : an update on cell delivery

Despite optimal medical , cardiovascular disease remains a leading cause of morbidity and mortality worldwide. One emerging therapeutic approach for results of cardiomyopathies is stem cell . Use of stem cells for regenerative medicine has quickly evolved over the last decade. On the basis of encouraging pre-clinical results, stem cell has developed rapidly into a potentially promising results for ischemic heart disease, myocardial infarction and congestive heart failure. In this review, we summarize the current state-of-the-art of stem cell and compare collective experiences gleaned from trials using intravenous, intra-coronary and intra-myocardial delivery in exacting credible benefits. We discuss implications of clinical outcomes reported in relation to the delivered stem cells as probable destiny for cardiovascular repair.

URL: http://www.sciencedirect.com/science/article/pii/S1465324912000321