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Human Placenta and Markers of Heavy Metals Exposure *

In their review, Esteban-Vasallo et al. (2012) discussed the use of human placenta to evaluate biomarkers of exposure to heavy metals. They correctly concluded that the use of placental tissue specimens to assess heavy metal exposure is actually underused. Surprisingly, they did not mention the well-documented relationship between mercury released from mercury-containing dental amalgam fillings and mercury disposition in placental tissues (Clarkson and Magos 2006; Gundacker and Hengstschläger 2012; Richardson et al. 2011).

Studies have suggested an association between mercury levels in placental tissues and the observed mercury dental amalgams in women (Ask et al. 2002; Palkovicova et al. 2008; Richardson et al. 2011). Elevated placental mercury levels have been reported in dental workers who, throughout pregnancy, were exposed to mercury vapor (Hg0) released during preparation of mercury amalgam in dental offices (Guzzi and Pigatto 2007; Wannag and Skjaeråsen 1975). As noted by Drasch et al. (1994), the mother-to-fetus transfer of mercury Hg0 from amalgams has been reported in human autopsy samples, and elevated levels of total mercury have been observed in the brain, liver, and kidney of human fetuses; these levels have been linked to the number of maternal amalgam-restored surfaces.

Transplacental exposure to heavy metals may affect child growth and cause neurodevelopmental delays. Thus, further efforts should be made to measure and quantify maternal exposure to heavy metals in placenta to estimate environmental prenatal exposure.


* Legal Disclaimer: Chelation and Hyperbaric Therapy, Stem Cell Therapy, and other treatments and modalities mentioned or referred to in this web site are medical techniques that may or may not be considered “mainstream”. As with any medical treatment, results will vary among individuals, and there is no implication or guarantee that you will heal or achieve the same outcome as patients herein.

As with any procedure, there could be pain or other substantial risks involved. These concerns should be discussed with your health care provider prior to any treatment so that you have proper informed consent and understand that there are no guarantees to healing.

THE INFORMATION IN THIS WEBSITE IS OFFERED FOR GENERAL EDUCATIONAL PURPOSES ONLY AND DOES NOT IMPLY OR GIVE MEDICAL ADVICE. No Doctor/Patient relationship shall be deemed to have arisen simply by reading the information contained on these pages, and you should consult with your personal physician/care giver regarding your medical treatment before undergoing any sort of treatment or therapy.

Published on 02-07-2015