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Use of Autologous Platelet-Rich Plasma (PRP) in Periodontal Defect Treatment After Extraction of Impacted Mandibular Third Molars New Jersey *

Purpose The extraction of mesioangular impacted third molars may cause multiple periodontal defects at the distal root of the second molar. Platelet-rich plasma (PRP) is a material containing many autologous growth factors that may be used in repairing and preventing periodontal complications at the distal root of the second molar adjacent to the extracted third molar.

Patients and Methods
We analyzed the effects of autologous PRP on periodontal tissues after extraction of the third molar in 18 young patients (age, 21–26 years). Inclusion criteria were the presence of a pocket distal to the mandibular second molar with a probing depth ≥7.5 mm and a probing attachment level ≥6 mm.

We observed, at 12 weeks after surgery, a notable reduction in the probing depth and an improvement in the probing attachment level in those cases treated with PRP compared with the controls, as well as formation of new bone tissue in the bone defect.

We showed that PRP is effective in inducing and accelerating bone regeneration for the treatment of periodontal defects at the distal root of the mandibular second molar after surgical extraction of a mesioangular, deeply impacted mandibular third molar.

* Legal Disclaimer: Chelation and Hyperbaric Therapy, Stem Cell Therapy, and other treatments and modalities mentioned or referred to in this web site are medical techniques that may or may not be considered “mainstream”. As with any medical treatment, results will vary among individuals, and there is no implication or guarantee that you will heal or achieve the same outcome as patients herein.

As with any procedure, there could be pain or other substantial risks involved. These concerns should be discussed with your health care provider prior to any treatment so that you have proper informed consent and understand that there are no guarantees to healing.

THE INFORMATION IN THIS WEBSITE IS OFFERED FOR GENERAL EDUCATIONAL PURPOSES ONLY AND DOES NOT IMPLY OR GIVE MEDICAL ADVICE. No Doctor/Patient relationship shall be deemed to have arisen simply by reading the information contained on these pages, and you should consult with your personal physician/care giver regarding your medical treatment before undergoing any sort of treatment or therapy.

Published on 06-01-2009
Authors: Gilberto Sammartino MDlow asterisk, Mariano Tia DMD†, Gaetano Marenzi MD‡, Alessandro Espedito di Lauro DMD§, Elio D’Agostino MDshort parallel and Pier Paolo Claudio MD, PhD¶,
Source: Journal of Oral and Maxillofacial Surgery Volume 63, Issue 6, June 2005, Pages 766-770