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Stem Cells Targeting Inflammation as Potential Anti-aging Strategies and Therapies *

Human aging is associated with a vast array of clinical disorders that all relate to the body’s inability to maintain homeostasis. In our bodies, the healing process requires tight control of the acute inflammatory response. When the levels of inflammatory markers such as interleukin-6, tumor necrosis factor alpha, and C-reactive protein are elevated, there is a direct correlation with several chronic diseases of aging such as cardiovascular disease, cognitive decline, and physical disability. Extensive studies have shown strong evidence that elevated levels of these pro-inflammatory mediators may predict disease and disability in the aging population. As there is no cure for aging, a key question is how to modulate the effects of inflammation on aging and how to maintain healthy aging. Stem cells offer alternative approaches for treating various diseases/disorders. The use of stem cells as immune system modulators has shown tremendous promise. Mesenchymal stem cells (MSCs) have specific immunomodulatory properties that may help control inflammation. Several animal studies demonstrate that intravenous infusions of MSCs can decrease the pro-inflammatory response while increasing the anti-inflammatory response. Moreover, human clinical studies using MSCs in autoimmune and other inflammatory diseases have demonstrated modulation of the inflammatory response. Therefore, the use of stem cells as anti-aging therapies may offer many an alternative method of slowing down or deterring several of the detrimental aspects of aging.

* Legal Disclaimer: Chelation and Hyperbaric Therapy, Stem Cell Therapy, and other treatments and modalities mentioned or referred to in this web site are medical techniques that may or may not be considered “mainstream”. As with any medical treatment, results will vary among individuals, and there is no implication or guarantee that you will heal or achieve the same outcome as patients herein.

As with any procedure, there could be pain or other substantial risks involved. These concerns should be discussed with your health care provider prior to any treatment so that you have proper informed consent and understand that there are no guarantees to healing.

THE INFORMATION IN THIS WEBSITE IS OFFERED FOR GENERAL EDUCATIONAL PURPOSES ONLY AND DOES NOT IMPLY OR GIVE MEDICAL ADVICE. No Doctor/Patient relationship shall be deemed to have arisen simply by reading the information contained on these pages, and you should consult with your personal physician/care giver regarding your medical treatment before undergoing any sort of treatment or therapy.

Published on 09-25-2017
Authors: Gonzalez, Rafael; Woynarowski, Dave; Geffner, Luis
Source: Cell & Tissue Transplantation & Therapy; London7 (2015): 1-8