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Stem Cell Treatment in Crohn’s Disease *

Crohn’s disease which mainly affects the gastrointestinal tract and impairs patient’s quality of life, is a refractory inflammatory disease with clinical manifestations of abdominal pain, fever, bowel obstruction and diarrhoea with blood or mucus. Besides the common complication of intestinal obstruction, the formation of fistulas should also be concerned about and anorectal fistula is the most typical. The disease is difficult to radical cure and easy to relapse, which urges people to find other effective treatment in addition to surgery. Given the challenges and prospective medical needs in Crohn’s fistula, attention has been directed at stem cell therapy. Several studies suggest that mesenchymal stem cells (MSCs) improve Crohn’s disease and Crohn’s fistula. In the recent years, a lot of studies of mesenchymal stem cell transplantation or local rejection with bone marrow-derived stem cells and adipose tissue-derived stem cells have been reported in the treatment of refractory Crohn’s disease and many of which are in remission. A number of clinical trials for refractory Crohn’s disease have also evaluated autologous or allogenic MSCs and have shown that MSCs can be safely administered with some patients achieving clinical response.

* Legal Disclaimer: Chelation and Hyperbaric Therapy, Stem Cell Therapy, and other treatments and modalities mentioned or referred to in this web site are medical techniques that may or may not be considered “mainstream”. As with any medical treatment, results will vary among individuals, and there is no implication or guarantee that you will heal or achieve the same outcome as patients herein.

As with any procedure, there could be pain or other substantial risks involved. These concerns should be discussed with your health care provider prior to any treatment so that you have proper informed consent and understand that there are no guarantees to healing.

THE INFORMATION IN THIS WEBSITE IS OFFERED FOR GENERAL EDUCATIONAL PURPOSES ONLY AND DOES NOT IMPLY OR GIVE MEDICAL ADVICE. No Doctor/Patient relationship shall be deemed to have arisen simply by reading the information contained on these pages, and you should consult with your personal physician/care giver regarding your medical treatment before undergoing any sort of treatment or therapy.

Published on 04-26-2017
Authors: Mrs. Xiao-mei Zhang, Miss Yu-jing Zhang, Dr. Wei Wang, Prof. Yu-quan Wei, Dr. Hongxin Deng