SERVICES*

Close-up TV News - Prolotheray lecture

Reversing Hypertension

Heavy Metals and all diseases

Close-Up TV News - Dr. Calapai's approach

News 12 Interview: Parkinson’s Disease, Glutathione and Chelation Therapy

News 12 Interview: Platelet-rich plasma therapy

Prolotherapy Interview News 12

News 12 Interview: Diabetes and Weight Loss
Mesenchymal Stem Cells Benefit Diabetes and Alzheimer’s Disease *

Type 2 diabetes mellitus (T2DM) is characterized by chronic hyperglycemia, which induces neuron, kidney and eye dysfunction. Hyperglycemia is also a risk factor for dementia. T2DM also causes brain insulin resistance, oxidative stress and cognitive impairment. Futhermore, oxidative stress causes a complex dysregulation of cell metabolism resulting in insulin resistance and beta cell dysfunction. Alzheimer’s Disease (AD) is the most common form of dementia among older people worldwide, and oxidative stress is an important pathogenic factor in AD. Oxygen metabolism generates free radicals such as hydroxylradical, superoxide radical, and reactive nitrogen species, inducing ROS. An imbalance between oxidant and antioxidant agents could generate oxidative stress, which damages macromolecules and disrupts the reduction/oxidation (redox) signaling. Mitochondria contain many redox enzymes, and generate ROS when there are inefficiencies in oxidative phosphorylation. Mitochondrial dysfunction occurs early and has a primary role in the pathogenesis of AD. T2DM patients show increased incidence of AD, and one report has shown the role of insulin in that it links T2DM with AD through mitochondrial alterations, oxidative stress and glucose metabolism. The insulin effect not only impacts glucose metabolism, but also has neuroprotective and neuromodulatory effects.

* Legal Disclaimer: Chelation and Hyperbaric Therapy, Stem Cell Therapy, and other treatments and modalities mentioned or referred to in this web site are medical techniques that may or may not be considered “mainstream”. As with any medical treatment, results will vary among individuals, and there is no implication or guarantee that you will heal or achieve the same outcome as patients herein.

As with any procedure, there could be pain or other substantial risks involved. These concerns should be discussed with your health care provider prior to any treatment so that you have proper informed consent and understand that there are no guarantees to healing.

THE INFORMATION IN THIS WEBSITE IS OFFERED FOR GENERAL EDUCATIONAL PURPOSES ONLY AND DOES NOT IMPLY OR GIVE MEDICAL ADVICE. No Doctor/Patient relationship shall be deemed to have arisen simply by reading the information contained on these pages, and you should consult with your personal physician/care giver regarding your medical treatment before undergoing any sort of treatment or therapy.

Published on 09-25-2017
Authors: Li Ming, Ikehara S