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Investigation of trace metals in the blood plasma and scalp hair of gastrointestinal cancer patients in comparison with controls *


Gastrointestinal cancer is one of the most common types of cancer which is predominantly associated with the environmental factors. The carcinogenic processes are linked with the imbalances of trace metals in body fluid and tissues.


Trace metals (Cd, Cr, Cu, Fe, Ni, Pb and Zn) are estimated in blood plasma and scalp hair of the cancer patients and controls employing nitric acid–perchloric acid based wet-digestion followed by atomic absorption spectrophotometric method.


The mean concentrations of Cd, Cr, Cu and Ni were found to be significantly higher in the plasma of patients compared with the controls, however, appreciably higher concentrations of Fe and Zn were observed in the plasma of controls. The average scalp hair concentrations of Zn, Fe, Pb, Cu and Cd were notably higher in the patients than controls. The correlation study revealed significantly different mutual variations of the trace metals in the plasma and scalp hair of the patients and controls. The apportionment of trace metals in the plasma and scalp hair of the patients and controls was also considerably different.


The study revealed that the carcinogenic processes are significantly affecting the trace metal burden and mutual variations in the cancerous patients compared with the controls.

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As with any procedure, there could be pain or other substantial risks involved. These concerns should be discussed with your health care provider prior to any treatment so that you have proper informed consent and understand that there are no guarantees to healing.

THE INFORMATION IN THIS WEBSITE IS OFFERED FOR GENERAL EDUCATIONAL PURPOSES ONLY AND DOES NOT IMPLY OR GIVE MEDICAL ADVICE. No Doctor/Patient relationship shall be deemed to have arisen simply by reading the information contained on these pages, and you should consult with your personal physician/care giver regarding your medical treatment before undergoing any sort of treatment or therapy.

Published on 02-14-2013