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Influence of micronutrients and related genes on colorectal cancer risk *

Abstract  Dietary factors are generally believed to be important determinants of risk of colorectal cancer, but the role of specific micronutrients remains controversial. The potential roles of B vitamins (especially folate and vitamin B6), vitamin D, and calcium are considered. Although much emphasis has been on the potential beneficial role of folate through one-carbon metabolism, recent evidence suggests an additional important role for vitamin B6.

Among micronutrients, the evidence for a benefit is strongest for calcium and vitamin D. Although the Women’s Health Initiative trial did not confirm the calcium and vitamin D hypotheses, critical issues with the design of the trial may have contributed to the null findings. The study of nutrient-gene interactions increases the biologic plausibility of a role of these micronutrients, especially for vitamin D.

* Legal Disclaimer: Chelation and Hyperbaric Therapy, Stem Cell Therapy, and other treatments and modalities mentioned or referred to in this web site are medical techniques that may or may not be considered “mainstream”. As with any medical treatment, results will vary among individuals, and there is no implication or guarantee that you will heal or achieve the same outcome as patients herein.

As with any procedure, there could be pain or other substantial risks involved. These concerns should be discussed with your health care provider prior to any treatment so that you have proper informed consent and understand that there are no guarantees to healing.

THE INFORMATION IN THIS WEBSITE IS OFFERED FOR GENERAL EDUCATIONAL PURPOSES ONLY AND DOES NOT IMPLY OR GIVE MEDICAL ADVICE. No Doctor/Patient relationship shall be deemed to have arisen simply by reading the information contained on these pages, and you should consult with your personal physician/care giver regarding your medical treatment before undergoing any sort of treatment or therapy.

Published on 10-30-2007