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Curcumin, Oxidative Stress, and Cancer Therapy *

Curcumin is the active ingredient in turmeric, a traditional herbal remedy and dietary spice. Curcumin has numerous beneficial medicinal properties, including cancer chemopreventive and cancer chemotherapeutic activity. Curcumin displays complex redox activity and functions as both pro- and antioxidant. These opposing activities are observed in cell-free systems, cultured cells, and in intact organisms. The redox properties of curcumin are a key feature of its activity and are due to the inherent chemical activities of the molecule, as well as its ability to induce multiple signaling pathways. This chapter provides an overview of the in vitro and in vivo studies that links curcumin’s redox activity to its chemopreventive and chemotherapeutic effects. It also highlights the need for caution in combining curcumin with certain chemotherapies or in the setting of selected preexisting conditions.

* Legal Disclaimer: Chelation and Hyperbaric Therapy, Stem Cell Therapy, and other treatments and modalities mentioned or referred to in this web site are medical techniques that may or may not be considered “mainstream”. As with any medical treatment, results will vary among individuals, and there is no implication or guarantee that you will heal or achieve the same outcome as patients herein.

As with any procedure, there could be pain or other substantial risks involved. These concerns should be discussed with your health care provider prior to any treatment so that you have proper informed consent and understand that there are no guarantees to healing.

THE INFORMATION IN THIS WEBSITE IS OFFERED FOR GENERAL EDUCATIONAL PURPOSES ONLY AND DOES NOT IMPLY OR GIVE MEDICAL ADVICE. No Doctor/Patient relationship shall be deemed to have arisen simply by reading the information contained on these pages, and you should consult with your personal physician/care giver regarding your medical treatment before undergoing any sort of treatment or therapy.

Published on 04-05-2013