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Chronic arsenic toxicity from Ayurvedic medicines *

Background Ayurvedic medicines are known to contain arsenic and concentrations up to toxic levels have been reported in certain formulations. However, clinical disease due to arsenic containing ayurvedic medicines has rarely been reported. We seek to highlight the existence of toxic levels of arsenic in certain ayurvedic preparations that can produce serious systemic manifestations.

Methods An 11-year-old girl developed manifestations of arsenical keratosis (punctuate palmoplantar keratoderma and leucomelanoderma) and non-cirrhotic portal hypertension, 6 months and 18 months respectively after intake of ayurvedic medications, prescribed for epilepsy. The eight ayurvedic preparations consumed by the patient and her serum levels were analyzed for arsenic content.

Results Arsenic content of ayurvedic medicines ranged from 5 mg/L to 248 mg/L. The serum arsenic level was 202.20 µg/L (normal < 60 µg/L). Skin manifestations improved after the discontinuation of ayurvedic medications.

Conclusions Ayurvedic medications should be consumed under strict guidance and supervision of qualified practitioners to prevent such catastrophies.

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As with any procedure, there could be pain or other substantial risks involved. These concerns should be discussed with your health care provider prior to any treatment so that you have proper informed consent and understand that there are no guarantees to healing.

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Published on 01-21-2011
Authors: Sujay Khandpur, MD (DERMAT), DNB (DERMAT), MNAMS, Amit K. Malhotra, MD (DERMAT), DNB (DERMAT), Vidhyut Bhatia, MD (PAED), Subandhu Gupta, DCH, Vinod K. Sharma, MD (DERMAT), MNAMS, Rakesh Mishra, MD (PAED), and Narendra K. Arora, MD (PAED), FAMS, FIAP, FIPHA
Source: International Journal of Dermatology