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Aluminum and copper in drinking water enhance inflammatory or oxidative events specifically in the brain *

Inflammatory and oxidative events are up-regulated in the brain of AD patients. It has been reported that in animal models of AD, exposure to aluminum (Al) or copper (Cu) enhanced oxidative events and accumulation of amyloid beta (Aβ) peptides. The present study was designed to evaluate the effect of a 3-month exposure of mice to copper sulfate (8 μM), aluminum lactate (10 or 100 μM), or a combination of the salts. Results suggest that although Al or Cu may independently initiate inflammatory or oxidative events, they may function cooperatively to increase APP levels.

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As with any procedure, there could be pain or other substantial risks involved. These concerns should be discussed with your health care provider prior to any treatment so that you have proper informed consent and understand that there are no guarantees to healing.

THE INFORMATION IN THIS WEBSITE IS OFFERED FOR GENERAL EDUCATIONAL PURPOSES ONLY AND DOES NOT IMPLY OR GIVE MEDICAL ADVICE. No Doctor/Patient relationship shall be deemed to have arisen simply by reading the information contained on these pages, and you should consult with your personal physician/care giver regarding your medical treatment before undergoing any sort of treatment or therapy.

Published on 10-27-2008
Authors: Angelica Becariaa, Debomoy K. Lahirib, Stephen C. Bondya, DeMao Chenb, Ali Hamadeha, Huihui Lia, Russell Taylora and Arezoo Campbella
Source: Journal of Neuroimmunology Volume 176, Issues 1-2, July 2006, Pages 16-23