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Concise Review: Mesenchymal Stem Cell Treatment of the Complications of Diabetes Mellitus

Mesenchymal stem cells (MSCs) are multipotent, self-renewing cells that can be found in almost all postnatal organs and tissues. The main functional characteristics of MSCs are their immunomodulatory ability, capacity for self-renewal, and differentiation into mesodermal tissues. The ability of MSCs to differentiate into several cell types, including muscle, brain, vascular, skin, cartilage, and bone cells, makes them attractive as therapeutic agents for a number of diseases including complications of diabetes mellitus. We review here the potential of MSCs as new therapeutic agents in the treatment of diabetic cardiomyopathy, diabetic nephropathy, diabetic polyneuropathy, diabetic retinopathy, and diabetic wounds. Also, in this review we discuss the current limitations for MSCs therapy in humans. STEM CELLS 2011;29:5–10

URL:  http://onlinelibrary.wiley.com/doi/10.1002/stem.556/full

Published on 01-31-2015

Comments by Dr. Calapai


Diabetes is a devastating degeneration of virtually all tissues of the body . Here in this
article the research shows stem cell benefits to a vast number of tissues and organs damaged by Diabetes.
I have seen this on my patient population.
So the stem cells work not only on the pancreas to help make more insulin producing cells , but also on the individual tissue and organ damage.

Posted on 2015-04-21 19:14:01

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