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Epstein-Barr virus and acute retinal necrosis in a 5-year-old immunocompetent child


To describe a case of bilateral acute retinal necrosis syndrome (ARNS) in a 5-year-old boy.


A retrospective, interventional case is described in one child attending the pediatric ophthalmology section, complaining of sudden bilateral red eye and haze-impaired vision. A standardized ophthalmologic examination and specific serological probes supported the diagnosis of severe bilateral ARNS in an immunocompetent child.


The reduced visual acuity (<20/400), the ocular fundus signs (perivasculitis, thrombosis and retinal edema) and the positive immunoglobulin M anti-Epstein Barr virus serology, lead us to the ARNS definitive diagnosis. Antiviral therapy (Acyclovir; Zovirax®), ciclopentolate dilating eye drops, and antiplatelet treatment (acetil salicylic acid; Aspirin®) were administered until recovering the final visual acuity (20/40).


The ARNS is an ocular disease with poor prognosis, which in turns may display better course when determining the etiopathogenic virus and selecting the appropriate and precocious therapy.

Published on 11-06-2009
Authors: Roberto Gallego-Pinazo,1,2 Miguel Harto,1 Jose J Garcia-Medina,2,3 Inmaculada Serra,1 Enrique Espa?a,1 and Maria D Pinazo-Duran2,4
Source: Clin Ophthalmol. 2008 June; 2(2),: 451?455.