Close-up TV News - Prolotheray lecture

Reversing Hypertension

Heavy Metals and all diseases

Close-Up TV News - Dr. Calapai's approach

News 12 Interview: Parkinson’s Disease, Glutathione and Chelation Therapy

News 12 Interview: Platelet-rich plasma therapy

Prolotherapy Interview News 12

News 12 Interview: Diabetes and Weight Loss
Seasonal Analyses of Air Pollution and Mortality in 100 US Cities

Time series models relating short-term changes in air pollution levels to daily mortality counts typically assume that the effects of air pollution on the log relative rate of mortality do not vary with time. However, these short-term effects might plausibly vary by season. Changes in the sources of air pollution and meteorology can result in changes in characteristics of the air pollution mixture across seasons. The authors developed Bayesian semiparametric hierarchical models for estimating time-varying effects of pollution on mortality in multisite time series studies.

The methods were applied to the database of the National Morbidity and Mortality Air Pollution Study, which includes data for 100 US cities, for the period 1987–2000. At the national level, a 10-µg/m3 increase in particulate matter less than 10 µm in aerodynamic diameter at a 1-day lag was associated with 0.15% (95% posterior interval (PI): –0.08, 0.39), 0.14% (95% PI: –0.14, 0.42), 0.36% (95% PI: 0.11, 0.61), and 0.14% (95% PI: –0.06, 0.34) increases in mortality for winter, spring, summer, and fall, respectively. An analysis by geographic region found a strong seasonal pattern in the Northeast (with a peak in summer) and little seasonal variation in the southern regions of the country. These results provide useful information for understanding particle toxicity and guiding future analyses of particle constituent data.

Published on 09-22-2008
Authors: Roger D. Peng1, Francesca Dominici1, Roberto Pastor-Barriuso2, Scott L. Zeger1 and Jonathan M. Samet3
Source: American Journal of Epidemiology Copyright © 2005 by the Johns Hopkins Bloomberg School of Public Health